Case Report: Clinical and Serological Hallmarks of Cytokine Release Syndrome in a Canine B Cell Lymphoma Patient Treated With Autologous CAR-T Cells
BackgroundChimeric antigen receptor-T (CAR-T) cells have transformed the treatment of human B cell malignancies.With the advent of CAR-T therapy, specific and in some cases severe toxicities have been documented with cytokine release syndrome (CRS) being the most frequently reported.As dogs develop tumors spontaneously and in an immunocompetent set